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Estudios recientes han proporcionado pruebas sólidas que sugieren que la colchicina es una opción de tratamiento eficaz para la pericarditis aguda y recurrente. Los farmacéuticos pueden desempeñar un papel vital para garantizar el tratamiento seguro y efectivo de la pericarditis aguda y recurrente. Tanto COPE como CORE revelaron que el uso previo de corticosteroides se asoció con un aumento de más del doble en las recurrencias adicionales9,10. Además, hubo una amplia gama de indicaciones incluidas, como gota, fiebre mediterránea familiar, enfermedad de Behcet y pericarditis, lo que conduce a una mayor generalización de los resultados del estudio. Los métodos utilizados en los estudios incluidos para evaluar los eventos adversos se describen en la Tabla complementaria 1. Reducir los efectos secundarios Fmf treatment usual ductal. colchicine NO incluye toda la información sobre los posibles usos, instrucciones, advertencias, precauciones, interacciones, efectos adversos o riesgos que pueden aplicarse a este medicamento. Esta información no es un consejo médico específico y no reemplaza la información que recibe del proveedor de atención médica. Debe hablar con el proveedor de atención médica para obtener información completa sobre los riesgos y beneficios de usar este medicamento. Se usa continuamente durante largos períodos de tiempo en individuos con fiebre mediterránea familiar y enfermedad de Behcet.La colchicina es un agente antiinflamatorio que se usa ampliamente para el tratamiento de la gota y también se usa ampliamente para la fiebre mediterránea familiar, la enfermedad de Behcet y la pericarditis.Sigue habiendo incertidumbre con respecto a su uso en ciertos grupos de riesgo, incluidos aquellos con insuficiencia renal y hepática, a dosis más altas y con inhibidores de CYP3A4.Su uso en el tratamiento de la gota ha aumentado debido a la recomendación generalizada de que se use como profilaxis de brote de gota cuando se inicia la terapia de reducción de urato.Sin embargo, debido a su largo uso histórico en medicina, no ha sido sometido a los mismos ensayos de registro que requieren las medicinas contemporáneas. Sobre colchicine la colchicina colchicine Actualmente no hay evidencia sobre si los AINE o la colchicina en dosis bajas es el mejor tratamiento para la gota aguda. Este ensayo será la primera comparación directa de la efectividad y los efectos secundarios de un AINE y la colchicina en dosis bajas para tratar la gota aguda en colchicine atención primaria. El naproxeno se usará en este ensayo porque se ha demostrado que es tan efectivo como la prednisolona oral para el tratamiento de la gota aguda, es más seguro que otros AINE utilizados comúnmente, como el diclofenaco y la indometacina, y es económico. Las cápsulas de 0,6 mg de colchicina están contraindicadas en pacientes con insuficiencia renal o hepática a quienes actualmente se les recetan medicamentos que inhiben tanto la P-gp como el CYP3A4. Pharmacy colchicine delivery fedex.
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