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Melatonin prevents the development of hyperplastic urothelium induced by repeated doses of cyclophosphamide.
The treatment remains challenging, but it could be interesting to investigate the potential efficacy of ibrutinib in BNS patients as this kinase inhibitor has recently been demonstrated to produce a high response rate in relapsed or refractory WM.
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Some of the patients also had chronic rhinitis runny nose and two patients developed warts, though these subsequently went away.
Evaluation of these preparation techniques, using fluorescent dye solutions, has shown contamination of gloves and the sleeves and chest of gowns.
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Identification of prognostic factors in 61 patients with posttransplantation lymphoproliferative disorders.
Dose-intensive therapies, infusional therapies, and stem cell transplantation consolidation are being explored in this high-risk group.
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Is something obvious to the future that we are not yet seeing about our current practice?
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Other approaches include the use of bone marrow transplantation for consolidation.
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Korn JH, Mayes M, Matucci CM, et al: Digital ulcers in systemic sclerosis: Prevention by treatment with bosentan, an oral endothelin receptor antagonist.
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This can have clinically important effects on cyclophosphamide and its cytotoxic metabolite 4-hydroxycyclophosphamide and thus both their therapeutic efficacy and side-effects.
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In judging the success of a treatment for NHL, the most important criteria are overall survival and the duration of time until the disease progresses or the patient dies.
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In conclusion, we found that a rituximab-based regimen was not superior to a conventional cyclophosphamide regimen when used as induction treatment in patients with ANCA-associated renal vasculitis.
Hematologic toxicity was the predominant adverse event, followed by fatigue, edema, and gastrointestinal symptoms.
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This increased risk remained even after the researchers accounted for diabetes risk factors such as smoking, physical activity levels, age, sex and obesity, and after the researchers excluded shift work, which increases the risk of obesity and diabetes.
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Whether circumcision can provide a protective benefit in men who engage in anal sex with a female partner remains equally inconclusive.
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Organizations acquired BSCs, gowns, gloves, and goggles, and implemented the recommendations in pharmacies and nursing units.
Stewart DJ, Morgan LR, Verma S, Maroun JA, Thibault M "Pharmacology, relative bioavailability, and toxicity of three different oral cyclophosphamide preparations in a randomized, cross-over study.
In such cases, the redness typically occurs more around the centre of the eye, close to the iris, and is largely absent from inside the lids, compared with the more peripheral redness of an allergy or infection.
There are many treatments for gout, including and non-prescription drugs; however, there are also many “home remedies” that can not only help prevent the buildup of crystallized uric acid that the kidneys fail to filter out, but also help alleviate the pain and discomfort once the condition has developed.
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Los investigadores sealaron que sus hallazgos corroboran estudios anteriores que sugeran que el trastorno bipolar podra ser mejor caracterizado como un trastorno de espectro.
Eosinophilic fasciitis is clinically distinguishable from the eosinophilia-myalgia syndrome and is not associated with L-tryptophan use.
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Sin embargo, los estudios de la FDA no han demostrado que los productos que figuran en la lista de medicamentos a retirar del mercado sean seguros y eficaces y por tanto no han sido debidamente aprobados.
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Biopsy-verified response of severe lupus nephritis to treatment with rituximab (anti-CD20 monoclonal antibody) plus cyclophosphamide after biopsy-documented failure to respond to cyclophosphamide alone.
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Nevertheless, Bratberg lamented, they are significantly underutilized.
As of the time of this publication, women under 17 still need a prescription for the drug; this could change at some point.
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Women 1840 may be eligible who have a uterine cervical sample that is HR HPV positive, have not received an active HPV vaccine at any time prior to the screening visit, and do not have evidence of genital, perianal or vaginal warts.
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Chronic inflammatory demyelinating polyneuropathy (CIDP) is an immune mediated disorder of the peripheral nervous system with clinical features that include weakness, sensory loss, imbalance, pain and impaired ambulation which may lead to substantial disability.
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Unrestricted educational grants from Novartis, Schering Health Care Ltd, Chugai, Pharmion, Celgene, and Ortho Biotech supported the trial coordination and the laboratory studies.
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Approximately 20% of cyclophosphamide is protein bound, with no dose dependent changes.
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The addition of trastuzumab to the chemotherapy regimen increased the frequency of leukopenia and anemia ().
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This is, therefore, extremely preliminary information and not an adequate basis for treatment decisions.
All patients gave informed consent according to institutional and federal guidelines before enrollment.
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